Global Health Equity Foundation, GHEF

Cardiovascular Disease (CVDs), Cerebrovascular Accident (CVAs), Type II Diabetes (T2DM) 

 Translational Initiatives

Cardiovascular disease (CVDs) remains the leading cause of mortality in the USA and other nations in the world. The understanding of the predisposing factors and the risk determinants in several subpopulations, such as racial/ethnic minorities in the US, especially blacks/African Americans (AA), American Indians (AI)/Alaska Natives (AN), Hispanics as well as Underserved Whites (UW) remain a pathway in subpopulations differentials in CVDs mortality marginalization and CVDs health equity transformation. Blacks/AA  are observed with the disproportionate burden of CVDs such as hypertension (HTn) in the US, with the risk determinants observed as the social determinants of health (SDH) as well as epigenomic determinants of health (EDH). The understanding of these specific HTn risk determinants, facilitates the pathway in excess comorbidities and mortality marginalizations in this subpopulation of blacks/AA.  


The GHEF remains an entity with translational initiatives that reflects a dynamic perspective based on the risk and predisposing factors in HTn incidence reduction in these subpopulations. The application of such data in intervention mapping and implementation facilitates risk reduction, low prevalence of HTn and marginalized mortality among racial/ethnic minorities in these subpopulations, hence global health improvement in CVDs as well as mortality reduction at a global level.  


Cerebrovascular accident (CVAs) remains the 3rd leading cause of mortality in the USA, with Blacks/AA   experiencing, the highest mortality, which is driven by CVDs such as unmanaged HTn.  The understanding of the risk and predisposing factors such as HTn as well as HTn , namely excessive alcohol consumption, physical inactivity, high fat diet, excessive sodium intake, sleep deprivation predispose to arterial stenosis and peripheral resistance, hence excessive cardiac output, namely stroke volume and cardiac rate. 

 The GHEF remains an entity with translational initiatives in the understanding of risk determinants and predisposing factors in these subpopulations as well as the application of intervention mapping and implementation in CVAs incidence reduction and mortality marginalization. 


Type II Diabetes (T2D) reflects a disproportionate burden of this disease among racial/ethnic minorities, namely Blacks/AA. The community needs assessment of the predisposing factors and risk determinants remain a reliable and accurate approach in T2D this incidence, prognosis such as lower extremities amputation and mortality remains a pathway in blood glucose level normalization and microvascular compromization, resulting in CVAs.   


With these morbidities incidence and prevalence dipartites reduction, the GHEF aims to assist the organization with interest in community health needs and prevention, implying GHEF community health needs survey as well as intervention mapping based on the reliable and accurate data in CVDs, CVAs and T2D health equity transformation.